基于数据挖掘技术探讨穴位疗法治疗甲状腺功能亢进症（简称甲亢）的临床选穴规律,为临床运用穴位疗法治疗甲亢提供思路。

计算机检索中国期刊全文数据库（CNKI）、维普资讯中文期刊服务平台（VIP）、万方数据知识服务平台（Wanfang）、中国生物医学文献数据库（SinoMed）、PubMed、Web of Science数据库中穴位疗法治疗甲亢的相关文献，检索时限为建库至2025年1月31日。建立Excel数据库并统计穴位处方，对文献类型、辨证分析、干预方法，以及腧穴使用频次、分布、归经和特定穴种类进行分析，运用SPSS Modeler 18.0、SPSS Statistics 21.0进行关联规则与聚类分析。

最终纳入52篇文献，涉及63个处方和78个穴位，腧穴总使用频次为520次。治疗甲亢的高频腧穴为内关（7.69%）、三阴交（7.31%）、足三里（7.12%）。总使用频次排名前5位的经脉分别是足阳明胃经（66次，12.69%）、手厥阴心包经（66次，12.69%）、足太阳膀胱经（62次，11.92%）、任脉（43次，8.27%）、足太阴脾经（42次，8.08%），腧穴主要分布于下肢部、头颈部及上肢部。治疗甲亢的78个腧穴中包含61个特定穴，其总使用频次为365次，占腧穴总使用频次的70.2%（365/520），其中总使用频次排名前3位的特定穴依次是五输穴、原穴、八脉交会穴。关联规则分析结果显示，当最低条件支持度为30%、最小规则置信度为80%时，得到22个组合，其中足三里-三阴交-内关组合关联性最强。聚类分析结果显示，树状图标度为20时，得到4组有效聚类群，分别为“三阴交-足三里-内关-阿是穴-间使”“大椎-风池”“合谷-水突-天突”“神门-太冲-太溪-复溜-肝俞”。

穴位疗法治疗甲亢以足阳明胃经腧穴为主，取穴以远部和近部选穴为主，重视特定穴的使用，遵循“上下配穴”原则，核心穴组为内关-三阴交-足三里。

To explore the clinical acupoint selection rules of acupoint therapy for hyperthyroidism based on data mining technology, so as to provide references for its clinical application.

Relevant literature on acupoint therapy for hyperthyroidism was retrieved from CNKI, VIP, Wanfang Data, SinoMed, PubMed and Web of Science, with the retrieval time ranging from the establishment of each database to January 31, 2025. An Excel database was established to collect acupoint prescriptions. Statistical analyses were performed on literature types, syndrome differentiation, intervention methods, as well as the frequency, distribution, meridian tropism and categories of specific acupoints. SPSS Modeler 18.0 and SPSS Statistics 21.0 were used for association rule analysis and cluster analysis.

A total of 52 eligible literatures were included, involving 63 prescriptions and 78 acupoints, with a total usage frequency of 520 times. The high-frequency acupoints for hyperthyroidism treatment were Neiguan (PC6, 7.69%), Sanyinjiao (SP6, 7.31%) and Zusanli (ST36, 7.12%). The top five meridians in terms of total usage frequency were the Stomach Meridian of Foot-Yangming (66 times, 12.69%), the Pericardium Meridian of Hand-Jueyin (66 times, 12.69%), the Bladder Meridian of Foot-Taiyang (62 times, 11.92%), the Conception Vessel (43 times, 8.27%) and the Spleen Meridian of Foot-Taiyin (42 times, 8.08%). Most acupoints were distributed in the lower extremities, head, neck and upper extremities. Among the 78 acupoints, 61 were specific acupoints, with a total frequency of 365 times, accounting for 70.2% (365/520) of the total. The top three specific acupoints were Five-Shu points, Yuan-source points and Eight Confluent Points. With the minimum support set at 30% and minimum confidence at 80%, 22 acupoint combinations were obtained via association rule analysis, among which the combination of Zusanli (ST36)-Sanyinjiao (SP6)-Neiguan (PC6) showed the strongest correlation. When the dendrogram scale was set at 20, four valid clusters were identified through cluster analysis: Sanyinjiao (SP6) -Zusanli (ST36) -Neiguan (PC6)-Ashi points-Jianshi (PC5), Dazhui (GV14)-Fengchi (GB20), Hegu (LI4)-Shuitu (ST10)-Tiantu (CV22), and Shenmen (HT7)-Taichong (LR3)-Taixi (KI3)-Fuliu (KI7)-Ganshu (BL18).

Acupoint therapy for hyperthyroidism mainly adopts acupoints of the Stomach Meridian of Foot-Yangming. Both distal and local acupoints are commonly selected with priority given to specific acupoints, following the principle of upper-lower acupoint matching. The core acupoint combination is Neiguan (PC6)-Sanyinjiao (SP6)-Zusanli (ST36).