膝骨关节炎是一种常见于中老年人的慢性退行性关节疾病，以关节疼痛肿胀、功能受限为核心表现，严重影响患者生活质量。目前膝骨关节炎的存在药物毒副作用明显、手术风险高等问题。倪光夏教授根据膝关节解剖特点，结合传统针灸理论，以内、外膝眼为主穴，采用长针深刺，并行多向互透治疗膝骨关节炎，起效迅速，可显著缓解疼痛，恢复关节功能，且疗效持久。本文介绍了该疗法的操作方法及临床验案，并探讨理论依据，以期为临床治疗膝骨关节炎提供新思路。

Knee osteoarthritis (KOA) is a prevalent chronic degenerative articular disorder predominantly affecting the middle-aged and elderly population, clinically characterized by articular pain, swelling, and motor dysfunction, which exerts a severe negative impact on patients' physical health and quality of life. At present, conventional pharmaceutical therapies for KOA are associated with notable adverse effects, while surgical interventions entail inherent high risks and potential postoperative complications. Based on the anatomical features of the knee joint and integrated with the theoretical connotations of traditional Chinese acupuncture and moxibustion, Professor Ni Guangxia has developed a targeted acupuncture therapy for KOA: taking Neixiyan (EX-LE4) and Waixiyan (EX-LE5) as the core acupoints, the therapy adopts long needles for deep puncture combined with multi-directional mutual penetration manipulation at the affected area. This acupuncture approach yields rapid therapeutic effects, can remarkably alleviate articular pain, effectively restore the motor function of the knee joint, and demonstrate durable curative efficacy in clinical practice. This paper elaborates on the standardized operational procedures and typical proven clinical cases of this therapy, and further explores its underlying theoretical basis and therapeutic mechanism, aiming to provide novel clinical insights and practical therapeutic strategies for the clinical diagnosis and treatment of knee osteoarthritis.