Current status of research on the mechanism of Xingnao Kaiqiao acupuncture for diseases of multipel systems

doi:10.3877/cma.j.issn.2095-3240.2023.04.003

Abstract

Abstract:

Xingnao Kaiqiao acupuncture is an innovative acupuncture method founded by master of Chinese medicine, academician Shi Xuemin, and this therapy takes the basic principle of curing the mind. The clinical efficacy has been confirmed by many studies, and its clinical application value is great. At present, although a large diagnostic and therapeutic system has been formed to treat stroke mainly by Xingnao Kaiqiao acupuncture, its inner mechanism has not been fully elucidated. In this review, by summarizing the possible mechanism of Xingnao Kaiqiao acupuncture in multiple systems, the mechanism of Xingnao Kaiqiao acupuncture in stroke, neurodegenerative diseases (vascular cognitive impairment, Parkinson′s disease), joint pain diseases, pediatric diseases, surgical diseases, endocrine and systemic diseases was preliminarily revealed, and the inner multidimensional effect pathways such as regulating related nerves, metabolism and inflammatory factors were explored. It is hoped to provide a reference for researchers to further explore the mechanism and connotation of Xingnao Kaiqiao acupuncture.

Key words: Consciousness restoring for resuscitation, Acupuncture therapy, Nervous system diseases

Zhihong Meng. Current status of research on the mechanism of Xingnao Kaiqiao acupuncture for diseases of multipel systems[J]. Chinese Journal of Acupuncture and Moxibustion(Electronic Edition), 2023, 12(04): 142-145.

/ / Recommend

Add to citation manager EndNote|Ris|BibTeX

URL: https://zhzjdzzz.cma-cmc.com.cn/EN/10.3877/cma.j.issn.2095-3240.2023.04.003

https://zhzjdzzz.cma-cmc.com.cn/EN/Y2023/V12/I04/142

References 38

1	Avan A, Digaleh H, Di Napoli M，et al.Socioeconomic status and stroke incidence, prevalence, mortality, and worldwide burden: an ecological analysis from the Global Burden of Disease Study 2017[J]. BMC Med, 2019, 17(1): 191.
2	D Kuriakose, Xiao Z. Pathophysiology and Treatment of Stroke: Present Status and Future Perspectives[J]. Int J Mol Sci, 2020, 21(20)．
3	高霄英，丁少杰，鲁海，等． "醒脑开窍"针刺法对中风患者实验室指标影响概述[J]．针灸临床杂志，2019, 35(12): 79－ 83.
4	王文秀，邱连利，刘倩，等． "醒脑开窍"针法对大脑中动脉闭塞大鼠不同时相ICAM－1、MMPs－9表达的影响[J]．针灸临床杂志，2020, 36(9): 61－ 65.
5	李倩． "醒脑开窍"针刺法对脑中风后遗症患者血清炎症因子及血管内皮功能的影响[J]. 陕西中医，2022, 43(1): 114－117.
6	刘春霞，李薇薇． "醒脑开窍"针刺法治疗缺血性脑卒中实验研究进展[J/CD]．中华针灸电子杂志，2015, 4(2): 10－13.
7	韩林，高旸，王旭慧，等．醒脑开窍针刺法对脑缺血再灌注损伤大鼠海马组织p－Akt(Ser473)表达及细胞凋亡的影响[J]. 天津中医药，2018, 35(8): 608－ 612.
8	庞青民，赵欲晓，邵素菊，等．醒脑开窍针刺法通过调控mTOR－EAAT2通路影响脑卒中后痉挛大鼠大脑皮层神经递质代谢[J]．中国病理生理杂志，2021, 37(11): 2001－2007.
9	韩林，高旸，王旭慧，等． "醒脑开窍"针刺法调节ATP敏感性钾通道开放对抗脑缺血再灌注损伤的机制研究[J]．中国针灸，2018, 38(12): 1319－1324.
10	吴松，杨悦悦，陈净，等．基于SystemXc－/GPX4轴调控的铁死亡在脑卒中后的研究进展[J]．医学研究与战创伤救治，2023，36(4)：436－ 441.
11	高莹，杨建．醒脑开窍针刺法对出血性卒中大鼠神经细胞铁死亡的影响[J]. 广西中医药大学学报，2023, 26(2): 40－ 45.
12	Ouerdane Y, Khlidj Y, Attia MS, et al. Calcitonin gene－related peptide: A biomarker for stroke in SARS－CoV－2 infection？[J]. Med Hypotheses, 2022, 162：110807.
13	许国超，张任．醒脑开窍针法治疗非痴呆性血管认知障碍临床研究[J]．针灸临床杂志，2019, 35(8): 8－12.
14	张任，荣兵，李建，等. 醒脑开窍针法对非痴呆性血管认知障碍的影响[J]．中医杂志，2019, 60(12): 1046－1050.
15	张其镇，苗雨，王大力，等．归脾汤加味联合醒脑开窍针法治疗非痴呆性血管认知障碍心脾不足证[J]．中国实验方剂学杂志，2019, 25(21): 66－71.
16	Yan XJ, Li YB, Liu W, et al. Predictive value of serum visinin－like protein－1 for early neurologic deterioration and three－month clinical outcome in acute primary basal ganglia hemorrhage: A prospective and observational study[J]. Clin Chim Acta, 2022, 531：62－ 67.
17	闵晓黎，王廷勇，刘佳，等．下调IGF－1通过CREB信号通路失活间接加重大鼠脑缺血损伤[J]．中风与神经疾病杂志，2015，32(10)：872－ 876.
18	Gong XQ, Ma MM, Fan XY, et al. Down－regulation of IGF－1/IGF－1R in hippocampus of rats with vascular dementia[J]. Neurosci Lett, 2012, 513(1): 20－24.
19	Taylor HA, Przemylska L, Clavane EM，et al. Meakin PJ. BACE1: More than just a β－secretase[J]. Obes Rev, 2022, 23(7): e13430.
20	Iadecola C．The pathobiology of vascular dementia[J]. Neuron, 2013, 80(4): 844－ 866.
21	Rosenberg GA.Extracellular matrix inflammation in vascular cognitive impairment and dementia[J]. Clin Sci (Lond), 2017, 131(6): 425－ 437.
22	陈娟．醒脑开窍针刺法对血管性痴呆患者IGF－1、MMP－2、MMP－9表达的影响[J]. 中医学报，2017, 32(10): 2022－2025.
23	夏凤玲，郭金金．醒脑开窍针法联合重复经颅磁刺激治疗脑梗死后血管性痴呆[J]．中医药临床杂志，2021, 33(8): 1502－1505.
24	袁媛，党宝齐，浦建能，等．重复经颅磁刺激联合醒脑开窍针法对脑梗死后血管性痴呆患者认知功能及日常生活能力的影响[J]. 现代中西医结合杂志，2020, 29(22): 2470－2473.
25	Deuel LM, Seeberger LC.Complementary Therapies in Parkinson Disease: a Review of Acupuncture, Tai Chi, Qi Gong, Yoga, and Cannabis[J]. Neurotherapeutics, 2020, 17(4): 1434－1455.
26	Ascherio A, Schwarzschild MA. The epidemiology of Parkinson′s disease: risk factors and prevention[J]. Lancet Neurol, 2016, 15(12): 1257－1272.
27	喇雪梅，郭媛，刘健，等.5－HT递质系统调节帕金森病精神症状和认知障碍的研究进展[J]．生理科学进展，2023，54(3)：177－184.
28	于佳佳．醒脑开窍针刺法联合重复经颅磁刺激治疗帕金森病临床观察[J]．光明中医，2022, 37(4): 659－ 662.
29	金梦雪，曹颖颖，郑群，等．当归四逆汤联合醒脑开窍针法对老年帕金森病患者MDA、CysC、SOD水平及生活质量的影响[J]．医学食疗与健康，2021，19(22)：37－38.
30	董正坤．针刺醒脑开窍联合中医辨证治疗颈性眩晕临床观察[J]．光明中医，2021, 36(6): 942－ 944.
31	李雅洁，田浩，安丽，等．醒脑开窍针刺法治疗丘脑痛：随机对照研究[J]. 中国针灸，2017, 37(1): 14－18.
32	谭郎敏，刘翠芳，范蕊，等．醒脑开窍针法治疗脑卒中后丘脑痛的疗效及对外周血5－HT、VIP、β－EP水平的影响[J]．川北医学院学报，2023, 38(2): 178－181.
33	何怡瀚，赵京霞，张冬梅，等．针刺镇痛领域国家自然科学基金资助情况报告与分析[J/OL]．中华针灸电子杂志，2023, 12(1): 1－7.
34	娄元俊，刘阳，单海军，等．针灸对脑性瘫痪幼鼠模型行为学的影响及其机制[J]. 中国组织工程研究，2016, 20(49): 7314－7319.
35	刘伟，李经纶．香蒲醒神汤联合醒脑开窍针应用于颅脑损伤术后昏迷患者[J]．实用中西医结合临床，2019, 19(9): 27－29.
36	汪大庆，张强，阴春霆，等．醒脑开窍汤对脑挫裂伤患者血清神经元特异性烯醇化酶的影响[J]．环球中医药，2015, 8(S1): 13－14.
37	许建霞．醒脑开窍针刺法对STBI急性期患者疗效及血浆S－100B、NSE、MBP、GFAP的影响[D]. 长沙：中南大学，2014.
38	李艳辉．洗心汤加减配合醒脑开窍针法治疗一氧化碳中毒后痴呆疗效观察[J]. 中医临床研究，2020, 12(32): 68－71.

[1]	Jingjing Wang, Feng Fu, Jianwei Li, Dangli Ren, Chong Chen, Hui Liu, Hongtao Sun, Yue Tu. Effect of acupuncture on BDNF/TrkB signaling pathway after moderate traumatic brain injury [J]. Chinese Journal of Neurotraumatic Surgery(Electronic Edition), 2023, 09(04): 199-205.
[2]	Qing Xiao, Cheng Wang, Kun Zhou, Yigong Wei. Technical principle and clinical application of brain-computer interface [J]. Chinese Journal of Brain Diseases and Rehabilitation(Electronic Edition), 2023, 13(04): 241-245.
[3]	Anna Jing, Bo Li, Yuzhen Wu, Ying Cui, Yuping Ma, Yuxian Li, Shiyi Jiang, Yutong Zhou. A study on the indications of Xingnao Kaiqiao acupuncture based on clinical evidence [J]. Chinese Journal of Acupuncture and Moxibustion(Electronic Edition), 2023, 12(04): 167-172.
[4]	Jing Ding, Peiwen Li, Yingchun Xu. The application of Xingnao Kaiqiao acupuncture in severe neurological emergencies [J]. Chinese Journal of Acupuncture and Moxibustion(Electronic Edition), 2023, 12(04): 161-164.
[5]	Ruiyu Li, Lingyong Xiao, Yuexin Zhang, Zhiying Li, Xiaoyu Dai. An analysis of the idea construction and protocol design of acupuncture timing study for the treatment of limb dysfunction in cerebral infarction using Xingnao Kaiqiao acupuncture [J]. Chinese Journal of Acupuncture and Moxibustion(Electronic Edition), 2023, 12(04): 156-160.
[6]	Shoufa Zhao, Shu Wang, Larissa Miare Vados, Alberto Cantidio Ferreira. Observation on the efficacy of Xingnao Kaiqiao acupuncture combined with rehabilitation therapy in the treatment of ischemic stroke in the recorvery period [J]. Chinese Journal of Acupuncture and Moxibustion(Electronic Edition), 2023, 12(04): 151-155.
[7]	Lina Ning, Jie Xiong. The therapeutic evaluation research on treating dysarthria after cerebral infarction with Xingnao Kaiqiao acupuncture and tongue acupuncture therapy [J]. Chinese Journal of Acupuncture and Moxibustion(Electronic Edition), 2023, 12(04): 146-150.
[8]	Zhilong Zhang. An analysis on treating spirit with Xingnao Kaiqiao acupuncture [J]. Chinese Journal of Acupuncture and Moxibustion(Electronic Edition), 2023, 12(04): 138-141.
[9]	Yuzheng Du. Development course of Xingnao Kaiqiao acupuncture and acupuncture and moxibustion siscipline in 50 years [J]. Chinese Journal of Acupuncture and Moxibustion(Electronic Edition), 2023, 12(04): 133-137.
[10]	Yuzheng Du, Lili Zhang, Yanan Zhang, Yinghui Chang. Explanation on International Standardized Manipulations of Chinese Medicine Xingnao Kaiqiao Acupuncture for Stroke [J]. Chinese Journal of Acupuncture and Moxibustion(Electronic Edition), 2023, 12(04): 173-176.
[11]	Xiumei Yin, Lihong Yang, Tao Jiang, Yuanhao Du. The exploration of the mechanism of Nestin in ischemic stroke and the effects of acupuncture based on neural stem cells [J]. Chinese Journal of Acupuncture and Moxibustion(Electronic Edition), 2023, 12(03): 111-116.
[12]	Yafei Ci, Mingxuan Guo, Chaoyang Liu, Duo Zhao. Clinical applications and analyses of different acupuncture directions at Fengchi(GB 20) [J]. Chinese Journal of Acupuncture and Moxibustion(Electronic Edition), 2023, 12(03): 129-132.
[13]	Hanzhang Liu, Zelin Chen. Clinical advances in the treatment of gouty arthritis with combination of acupuncture and medicine [J]. Chinese Journal of Acupuncture and Moxibustion(Electronic Edition), 2023, 12(02): 86-88.
[14]	Keqin Huan, Shuqiang Ding. Advances in clinical treatment of Guillain-Barré syndrome [J]. Chinese Journal of Acupuncture and Moxibustion(Electronic Edition), 2023, 12(02): 54-56.
[15]	Haijie Gao, Baojun Wang. Advance in the relationship between TLR4 signaling pathway and nervous system diseases [J]. Chinese Journal of Cerebrovascular Diseases(Electronic Edition), 2023, 17(01): 61-65.

Please choose a citation manager

Content to export