Recent years, acupuncture therapy shows obvious advantages in the treatment of common diseases in clinic. The acupuncture treatment of " unblocking the conception vessel and regulating qi" (Tongren Shunqi) is a new therapy which has been summed up during rich long-term clinical practice, which can cure many diseases. This acupuncture therapy, with some advantages over the conventional acupuncture treatments, has significant clinical effects. This paper introduces these clinical effects of the acupuncture treatment of " unblocking the conception vessel and regulating qi" , by taking post stroke depression, post stroke insomnia and cardiac neurosis for example.