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中华针灸电子杂志 ›› 2024, Vol. 13 ›› Issue (01) : 25 -29. doi: 10.3877/cma.j.issn.2095-3240.2024.01.007

文献研究

针刺辨证治疗血管性痴呆的选穴规律研究
杨晨1, 王松涛2, 郭涛2, 邱继文3,()   
  1. 1. 301617 天津中医药大学针灸推拿学院
    2. 301617 天津中医药大学实验针灸学研究中心
    3. 301617 天津中医药大学针灸推拿学院;301617 天津中医药大学实验针灸学研究中心;300381 天津,国家中医针灸临床医学研究中心
  • 收稿日期:2023-02-23 出版日期:2024-02-15
  • 通信作者: 邱继文
  • 基金资助:
    国家自然科学基金(81904295)

Study on the rules of acupoints selection in the treatment of vascular dementia by syndrome differentiation and acupuncture treatment

Chen Yang1, Songtao Wang2, Tao Guo2, Jiwen Qiu3,()   

  1. 1. School of Acupuncture and Moxibustion and Tuina, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
    2. Experimental Acupuncture Research Center, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
    3. School of Acupuncture and Moxibustion and Tuina, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China; Experimental Acupuncture Research Center, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China; National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China
  • Received:2023-02-23 Published:2024-02-15
  • Corresponding author: Jiwen Qiu
引用本文:

杨晨, 王松涛, 郭涛, 邱继文. 针刺辨证治疗血管性痴呆的选穴规律研究[J]. 中华针灸电子杂志, 2024, 13(01): 25-29.

Chen Yang, Songtao Wang, Tao Guo, Jiwen Qiu. Study on the rules of acupoints selection in the treatment of vascular dementia by syndrome differentiation and acupuncture treatment[J]. Chinese Journal of Acupuncture and Moxibustion(Electronic Edition), 2024, 13(01): 25-29.

目的

探讨针刺辨证治疗血管性痴呆(VD)的选穴规律。

方法

检索中国期刊全文数据库(CNKI)、万方数据知识服务平台(Wanfang)、维普资讯中文期刊服务平台(VIP)数据库中针刺辨证选穴治疗VD的相关文献,检索时限为2012年1月1日至2022年12月31日。采用Microsoft Excel 2016进行数据整理,应用SPSS Modeler18.0软件和SPSS 26.0软件分析针刺辨证治疗VD的选穴规律。

结果

(1)最终纳入48篇文献,共涉及17种证型,可归为实证、虚证及虚实夹杂证三大类,其中实证以痰蒙清窍证、瘀血阻络证最为常见,虚证以肾精亏虚证、肝肾亏虚证及气血亏虚证最为常见,虚实夹杂证以气虚血瘀证最为常见。(2)使用频次位居前十位的腧穴分别为神庭、百会、四神聪、水沟、足三里、三阴交、太溪、肾俞、风池、血海。(3)穴位关联度最高的组合为百会-神庭-四神聪。(4)聚类分析共得到5个有效聚类群。

结论

针刺治疗VD以辨证论治为基本原则,以"百会-神庭-四神聪"为主穴,在此基础上辨证选穴治疗。实证配以"水沟-大椎-风府""气海-血海-足三里",具体辨证加用丰隆、内关等穴;虚证配以"太溪-三阴交-肾俞""气海-血海-足三里",具体辨证加用肝俞、膈俞等穴;虚实夹杂证兼有实证、虚证的特点,兼有二者之用穴,虚则补之,实则泻之。

Objective

To explore the rules of acupoints selection based on syndrome differentiation and acupuncture treatment of vascular dementia.

Methods

The acupuncture treatment of vascular dementia based on syndrome differentiation was searched from CNKI, Wanfang and VIP databases. The search period was from Januare 1st of 2012 to December 31st of 2022.The data was organized using Microsoft Excel 2016, managed using SPSS Modeler 18.0 and SPSS 26.0 to analyze the acupoint selection rule based on syndrome differentiation and acupuncture treatment.

Results

(1)Forty-eight literatures were finally included concerning 17 types of syndrome, and the syndrome could be classified as deficiency syndrome, excess syndrome, deficiency-excess complication syndrome.Among them, the most common excess syndrome are syndrome of phlegm obscuring and clearing the orifices, and syndrome of blood stasis blocking collaterals, the most common deficiency syndrome are kidney essence deficiency syndrome, liver and kidney deficiency syndrome, qi and blood deficiency syndrome, the most common deficiency-excess complication syndromeis qi deficiency and blood stasis syndrome.(2)The top ten acupoints were Shenting(DU 24), Baihui(DU 20), Sishencong(EX-HN1), Shuigou(DU 26), Zusanli(ST 36), Sanyinjiao(SP 6), Taixi(KI 3), Shenshu(BL 23), Fengchi(CB 20) and Xuehai(SP 10). (3)The most correlated acupoints combination is " DU 20-DU 24-EX-HN1". (4)Cluster analysis yielded atotal of five effective clusters.

Conclusions

The treatment of acupuncture for vascular dementia is based on syndrome differentiation, with " DU 20, -DU 24-EX-HN1" as the main points.The matching points of excess syndrome are " DU 26-DU 14-DU 16, ", " RN 6-SP 10-ST 36, " and add ST 40 and PC 6 according to syndrome differentiation.The matching points of deficiency syndrome are " KI 3-SP 6-BL 23", " SP 10-ST 36", and add Ganshu(BL 18) and Geshu(BL 17) according to syndrome differentiation.Deficiency-excess complication syndrome has the characteristics of both, sothe acupoints mentioned above were applied, to treating deficiency syndrome with tonifying method, as well as treating excess syndrome with purgative method.

图1 针刺辨证治疗血管性痴呆临床研究文献筛选流程
图2 血管性痴呆各证型出现频次统计
表1 常见具体辨证选穴(≥5次)
表2 针刺辨证治疗血管性痴呆高频穴位关联规则分析
图3 针刺辨证治疗血管性痴呆应用频次≥10的穴位关联规则网络图
图4 高频穴位聚类谱系图
1
Bir SCKhan MWJavalkar V,et al.Emerging Concepts in Vascular Dementia:A Review[J].J Stroke Cerebrovasc Dis202130(8):105864.
2
Tonomura S, Gyanwali B. Cerebral microbleeds in vascular dementia from clinical aspects to host-microbial interaction[J].Neurochem Int, 2021148:105073.
3
Deardorff WJGrossberg GT.Behavioral and psychological symptoms in Alzheimer′s dementia and vascular dementia[J].Handb Clin Neurol, 2019165:5-32.
4
王倩.血管性痴呆的临床研究进展[J].医疗装备202134(10):189-191.
5
Harris MLTitler MGStruble LM.Acupuncture and Acupressure for Dementia Behavioral and Psychological Symptoms: A Scoping Review[J]. West J Nurs Res202042(10):867- 880.
6
国家市场监督管理总局,国家标准化管理委员会.中医临床诊疗术语第2部分:证候[S].北京:中国标准出版社,2021.
7
石莹莹,胡晓灵.阿尔茨海默病的中医文献研究[J].新疆中医药201735(1):63- 66.
8
程红亮,殷红彪,胡培佳,等.电针井穴对血管性痴呆大鼠海马CA1区ERK表达的影响[J].时珍国医国药201728(7):1792-1794.
9
秦懿囡,王利然,谢玥,等.近10年针灸治疗血管性痴呆的优势方案筛选研究[J].中华中医药杂志202035(8):4109- 4112.
10
冯琪,尚华杰,臧颖颖,等.针灸治疗血管性认知障碍的研究进展[J].长春中医药大学学报201834(1):192-195.
11
彭静,陈曦. "补肾通督,醒脑益智"法电针治疗血管性痴呆80例[J].中国针灸202242(6):623- 624.
12
马雪梅.益气调神针法治疗轻、中度血管性痴呆的临床观察[D].北京中医药大学,2018.
13
张鑫,李敏,彭晓燕,等.百会穴、大椎穴在血管性痴呆治疗中的作用机制探讨[J].辽宁中医杂志201744(4):835- 838.
14
石涛,韩东岳,李铁,等.四神聪穴的现代应用规律总结[J].长春中医药大学学报201228(4):695- 696.
15
李选,姚娓,原亚利,等.督脉治疗血管性痴呆临床应用探讨[J].辽宁中医药大学学报202123(4):149-153.
16
乔一琦,李敏,万婷.头项部腧穴在针灸治疗血管性痴呆中应用规律的探讨[J].辽宁中医杂志201946(9):1937-1940.
17
王琪,李澎,许军峰.针刺水沟穴治疗缺血性脑损伤机制研究进展[J].针灸临床杂志202137(7):88- 91.
18
王芝,张君.大椎穴的穴性及其临床运用[J].中医研究201932(7):50-51.
19
周黎,李智杰,金海涛.补肾化痰法针刺改善血管性痴呆患者日常生活能力及中医证候疗效观察[J].针灸临床杂志201329(1):4-7.
20
王珩,杨雪,刘月姣.涌泉穴为主温针灸治疗血管性痴呆(肾精亏虚证)的疗效及对患者认知功能、血清IL- 8、TNF-α、Livin水平的影响[J].四川中医202139(12):207-210.
21
郭芳芳,陆晖.血管性痴呆的病因病机研究进展[J].中医临床研究20179(29):138-141.
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