切换至 "中华医学电子期刊资源库"

中华针灸电子杂志 ›› 2023, Vol. 12 ›› Issue (02) : 62 -66. doi: 10.3877/cma.j.issn.2095-3240.2023.02.006

综述

针灸抗衰老在骨科相关退行性疾病的研究现状
梁兴森1, 高彦平2, 李嘉3, 李玲4, 郑小飞5, 王华军5,()   
  1. 1. 510500 广州,广州体育学院运动医学康复中心
    2. 510630 广州,南方医科大学第三附属医院中医骨伤科
    3. 510080 广州,广东省人民医院(广东省医学科学院)正骨科
    4. 510080 广州,广东省人民医院(广东省医学科学院)风湿免疫科
    5. 510630 广州,暨南大学附属第一医院骨关节与运动医学中心
  • 收稿日期:2022-12-18 出版日期:2023-05-15
  • 通信作者: 王华军
  • 基金资助:
    国家自然科学基金项目(82074511, 81973660); 广东省中医药局中医药科研项目(20202040); 暨南大学附属第一医院临床前沿新技术项目(JNU1AF-CFTP-2022-a01204)

Current status of acupuncture and moxibustion against aging in orthopedics related degenerative diseases

Xingsen Liang1, Yanping Gao2, Jia Li3, Ling Li4, Xiaofei Zheng5, Huajun Wang5,()   

  1. 1. Sports Medicine Rehabilitation Center, Guangzhou Sport University, Guangzhou 510500, China
    2. Department of Traditional Chinese Medicine Orthopedics & Traumatology, the Third Affiliated Hospital of Southern Medical University, Guangzhou 510630, China
    3. Department of Traditional Chinese Medicine Bone-Setting, Guangdong Provincial People’s Hospital(Guangdong Academy of Medical Sciences), Guangzhou 510080, China
    4. Division of Rheumatology, Guangdong Provincial People’s Hospital(Guangdong Academy of Medical Sciences), Guangzhou 510080, China
    5. Department of Orthopedics, the First Affiliated Hospital of Jinan University, Guangzhou 510630, China
  • Received:2022-12-18 Published:2023-05-15
  • Corresponding author: Huajun Wang
引用本文:

梁兴森, 高彦平, 李嘉, 李玲, 郑小飞, 王华军. 针灸抗衰老在骨科相关退行性疾病的研究现状[J]. 中华针灸电子杂志, 2023, 12(02): 62-66.

Xingsen Liang, Yanping Gao, Jia Li, Ling Li, Xiaofei Zheng, Huajun Wang. Current status of acupuncture and moxibustion against aging in orthopedics related degenerative diseases[J]. Chinese Journal of Acupuncture and Moxibustion(Electronic Edition), 2023, 12(02): 62-66.

退行性关节炎、骨质疏松、增龄性肌肉松弛、椎间盘变性等骨科相关退行性疾病均与衰老有关,虽然人体的老化趋势不能改变,但是可以采用一定方法改善各系统的功能以减缓老化速度,从而预防或医治老年疾病以提高生存质量。关于衰老,中医学和现代医学都有丰富的理论和学说。绿色安全的针灸疗法得到全世界的普遍认可,国内外均有针灸抗衰老方面的基础及临床研究。检索近年来关于针灸抗衰老在骨科相关退行性疾病方面的研究报道,对其作用机制进行总结概述,并分析既往研究存在的不足,以期为针灸抗衰老的进一步实验研究或临床应用提供借鉴。

Degenerative arthritis, osteoporosis, age-related muscle relaxation, intervertebral disc degeneration and other musculoskeletal degenerative diseases in orthopedics are all related to aging. Although aging can not be reversed, certain methods be adopted to improve the functions of various systems to delay aging, so as to prevent or cure geriatric diseases and improve life quality. There are abundant theories or doctrines about aging in both traditional Chinese medicine and modern medicine. The safe acupuncture treatment has been widely recognized all over the world, and there are basic and clinical researches on acupuncture and moxibustion anti-aging roles at home and abroad. The recent reports on anti-aging effects of acupuncture on musculoskeletal degenerative diseases were searched, the related mechanism was summarized, and deficiency of previous studies were analyzed, with a view to providing ideas or reference for further experimental research or clinical application of acupuncture on anti-aging.

1
Chen LK.Urbanization and population aging: Converging trends of demographic transitions in modern world[J].Arch Gerontol Geriatr2022101:104709.
2
李怡,李学智,廖冬梅,等.基于MCP-1/MMP-2/TGF-β1局部促炎信号环探讨温和灸对老年大鼠血管衰老的干预作用[J].针刺研究202247(4):290-297.
3
温佩彤,徐平,虎力,等.电针结合有氧运动对自然衰老大鼠骨骼肌IGF-I/Akt通路的作用[J].中国骨伤202134(3):275-281.
4
曾婷婷,姚太万,李学智,等.电针对睾酮低下老年大鼠睾丸间质细胞抗氧化功能的影响[J]. 针刺研究201944(8):566-570,582.
5
靖媛,张苗,游世晶,等.艾灸关元穴对D-半乳糖诱导的衰老大鼠皮肤氧化应激及MMP-1、TIMP-1 mRNA表达的影响[J].福建中医药201849(5):32-35.
6
毛佳楠,罗伟,王莉灵,等.朱琏缓慢捻进法对衰老大鼠超氧化物歧化酶表达的影响[J].中国老年学杂志202242(14):3522-3526.
7
Yang XWang WZhang Y,et al.Moxibustion improves ovary function by suppressing apoptosis events and upregulating antioxidant defenses in natural aging ovary[J]. Life Sci2019229:166-172.
8
Liu JLiu JXiao L,et al.Identification of differentially expressed miRNAs in the response of spleen CD4+ T cells to electroacupuncture in senescence-accelerated mice[J].Cell Biochem Biophys202078(1):89-100.
9
Jiang LJing HLan L,et al.Effects of acupuncture combined with exercise on expression of immune factors in aging rats and its significance in antiaging intervention[J].Comput Math Methods Med20222022:6833196.
10
杨健濠,卢美静,赵彩娇,等.灵龟八法按时开穴灸对衰老大鼠免疫功能及核因子-κB信号通路的影响[J].针刺研究202045(12):980-984.
11
马琳,李学智,姚太万,等.不同针灸疗法对老年雄性大鼠下丘脑-睾丸中生殖激素调控系统相关基因表达的影响[J].针刺研究201944(3):200-219.
12
杨云昊,庞芳,黄思琴,等.电针对快速衰老小鼠肝脏自噬及脂质代谢的影响[J].中国应用生理学杂志202137(4)365-370.
13
杨云昊,陶春鹤,庞芳,等.电针通过调节AMPK/mTOR/ULK1信号通路对衰老小鼠肝脏自噬与氧化应激的影响[J].针刺研究202247(1):7-14.
14
Hu WJing YYu Q,et al.Differential gene screening and bioinformatics analysis of epidermal stem cells and dermal fibroblasts during skin aging[J].Sci Rep202212(1):12019.
15
Liu NJiang YXing M,et al.Digital Gene Expression Profiling Analysis of Aged Mice under Moxibustion Treatment[J].Evid Based Complement Alternat Med20182018:4767328.
16
Zhou MYuan YLin Z,et al.Acupoint catgut embedding improves senescence in a rat model of ageing by regulating mitophagy via the PINK1 pathway[J].J Cell Mol Med202125(8):3816-3828.
17
王瑜,杨健濠,赵彩娇.灵龟八法艾灸对衰老大鼠肝脏端粒长度及细胞周期调节因子表达的影响[J].针刺研究202146(2):117-122.
18
Chang SGuo XLi G,et al.Acupuncture promotes expression of Hsp84/86 and delays brain ageing in SAMP8 mice[J].Acupunct Med201937(6):340-347.
19
Kaku NShimada TTanaka A,et al.Ultrastructure and three-dimensional architecture of the anterior cruciate ligament in the knee joints of young and old monkeys[J].Med Mol Morphol202053(1):7-14.
20
Zullo AFleckenstein JSchleip R,et al.Structural and functional changes in the coupling of fascial tissue, skeletal muscle, and nerves during aging[J].Front Physiol202011:592.
21
He SZhou XYang G,et al. Proteomic comparison between physiological degeneration and needle puncture model of disc generation disease[J]. Eur Spine J202231(11):2920-2934.
22
Du J, Xu M, Kong F, Zhu P,et al. CB2R attenuates intervertebral disc degeneration by delaying nucleus pulposus cell senescence through AMPK/GSK3β Pathway[J]. Aging Dis202213(2):552-567.
23
朱正威,唐成林,李小宏,等.电针对衰老性肌萎缩小鼠腓肠肌中促血管生成和蛋白转运相关因子的影响[J].针刺研究202045(12):973-979.
24
Soares Mendes Damasceno GTeixeira THMMde Souza VC,et al. Acupuncture treatment in elderly people with sarcopenia: effects on the strength and inflammatory mediators[J].J Aging Res20192019:8483576.
25
黄宏兴,史晓林,李盛华,等.肌少-骨质疏松症专家共识[J].中国骨质疏松杂志202211(1):1-18.
26
权兴苗,王月,宋春侠,等.针灸对自然衰老围绝经期大鼠雌激素水平及单胺类神经递质的影响[J].中国老年学杂志202242(11):2745-2749.
27
Geng ZLiu PYuan L,et al.Electroacupuncture attenuates ac4C modification of P16 mRNA in the ovarian granulosa cells of a mouse model premature ovarian failure[J]. Acupunct Med202341(1):27-37.
28
Yao CZhao CZhang S,et al.Effect of moxibustion on testosterone secretion and apoptosis of spermatogenic cells in aging rats[J].Evid Based Complement Alternat Med20192019:5186408.
29
曾婷婷,李学智,唐成林,等.电针对睾酮低下老年大鼠Keap1-Nrf2/ARE信号通路的影响[J].中国中西医结合杂志202141(11):1359-1364.
[1] 林文, 王雨萱, 许嘉悦, 王矜群, 王睿娜, 何董源, 樊沛. 人工关节置换登记系统的研究进展[J]. 中华关节外科杂志(电子版), 2023, 17(06): 834-841.
[2] 卫杨文祥, 黄浩然, 刘予豪, 陈镇秋, 王海彬, 周驰. 股骨头坏死细胞治疗的前景和挑战[J]. 中华关节外科杂志(电子版), 2023, 17(05): 694-700.
[3] 唐林, 吴颖斌, 潘恩豪, 卢伟杰. 发育性髋关节发育不良全髋置换髋臼假体放置的研究进展[J]. 中华关节外科杂志(电子版), 2023, 17(01): 65-70.
[4] 姜博庸, 韩长旭. 间充质干细胞外泌体促进软骨再生的潜在机制研究[J]. 中华关节外科杂志(电子版), 2023, 17(01): 44-51.
[5] 占一姗, 朱友荣, 张守华, 陶强. 急性阑尾炎相关诊断预测模型的研究进展[J]. 中华普通外科学文献(电子版), 2023, 17(02): 151-154.
[6] 王小兵, 邓卓凡, 龚建平. 肝细胞癌自发性破裂出血危险因素及预测模型研究现状[J]. 中华肝脏外科手术学电子杂志, 2023, 12(01): 29-33.
[7] 张智龙. 醒脑开窍针刺法治神思想钩玄[J]. 中华针灸电子杂志, 2023, 12(04): 138-141.
[8] 苏慧媛, 宋洪涛, 高巍, 武忠. 针刺治疗单纯性肥胖的系统评价和Meta分析[J]. 中华针灸电子杂志, 2023, 12(03): 123-128.
[9] 潘丽佳, 潘茹芳, 李青敏, 张晓琪, 贾春生. 艾灸辅助治疗恶性肿瘤的临床研究进展[J]. 中华针灸电子杂志, 2023, 12(01): 24-26.
[10] 史亚东, 顾建平. 无症状肺栓塞的诊断与治疗进展[J]. 中华介入放射学电子杂志, 2023, 11(02): 155-158.
[11] 陈静, 逯艳艳, 徐耀东, 马颖才. 联动成像技术在肠道病变中的研究进展[J]. 中华胃肠内镜电子杂志, 2023, 10(03): 195-199.
[12] 桑素娟, 王盈盈, 李丽楠, 刘晓冰, 雷燕妮, 程艳爽. 胃管抽吸物pH测试法用于胃管位置定位的研究进展[J]. 中华胃肠内镜电子杂志, 2023, 10(02): 131-135.
[13] 王擎, 王冠峰, 陈星. 胃食管阀瓣的Hill分级在胃食管反流病中的应用价值[J]. 中华胃肠内镜电子杂志, 2023, 10(02): 125-130.
[14] 王翊钊, 刘阳, 叶淑君, 马连君. 胃食管反流病治疗的研究进展[J]. 中华胃肠内镜电子杂志, 2023, 10(01): 57-61.
[15] 买买提·依斯热依力, 尹强, 尹海龙, 董雨微, 王永康, 克力木·阿不都热依木, 阿吉艾克拜尔·艾萨. 传统医药治疗胃食管反流病的研究进展[J]. 中华胃食管反流病电子杂志, 2023, 10(02): 100-104.
阅读次数
全文


摘要