目的

探讨樗木皮液外用治疗带状疱疹的临床疗效。

方法

选取2011年1月至2014年10月山东省威海市文登中心医院康复医学科带状疱疹患者148例，按照随机数字表法将148例患者随机分为两组，治疗组78例，对照组70例。对照组给予更昔洛韦0.25 g/d静脉滴注治疗，治疗组在对照组治疗基础上另给予樗木皮液外用治疗。10 d为1个疗程，治疗1个疗程后，按照《中医病证疗效标准》进行疗效评价，并分别于治疗前和治疗后采用视觉模拟评分法（VAS）进行疼痛程度评估，比较两组患者VAS疼痛评分、止疱时间、结痂时间、皮损消失时间以及治疗有效率间的差异。采用SPSS17.0统计学软件进行数据分析。两组患者治疗前后VAS疼痛评分、止疱时间、结痂时间、皮损消失时间为计量资料且呈正态分布，以 表示，两组间比较采用两独立样本t检验；其余资料为计数资料，统计分析采用卡方检验。P＜0.05为差异有统计学意义。

结果

治疗组治愈62例，好转14例，总有效率97.44%（76/78）。对照组治愈41例，好转20例，总有效率87.14%（61/70）。两组有效率比较，差异有统计学意义（χ²=9.390，P＜0.05）。两组患者治疗后VAS疼痛评分、疼痛消失时间、结痂和皮损消退时间比较，差异均有统计学意义（t=2.582、2.214、2.107、2.188，均P＜0.05）。

结论

樗木皮液外用治疗带状疱疹具有显著疗效。

Objective

To investigate the clinical effect of Ailanthus bark liquid for external treatment of herpes zoster.

Methods

A total of 148 patients with herpes zoster were selected in the department of rehabilitation medicine of Wendeng Central Hospital from January 2011 to October 2014.Patients were randomly divided into two groups according to the random number table method. The treatment group included 78 patients and control group included 70 cases. The treatment of 0.25 g/d ganciclovir intravenous infusion was given to control group. The treatment group was given Ailanthus veneer liquid and 0.25 g/d ganciclovir intravenous infusion. After one course (10 days) treatment,the therapeutic effect was evaluated according to the standard of efficacy of traditional Chinese medicine ( TCM ). The visual analog scale ( VAS ) was used to evaluate the degree of pain before and after treatment. VAS pain score, time of stop blister scab, scabby time, time of skin lesion disappeared and the difference of treatment efficacy were compared between two groups. SPSS17.0 software was used to analyze the data. Data of VAS pain score, time of stop blister scab, scabby time,time of skin lesion disappeared before and after treatment were normal distribution and expressed as χ±s . T-test was used for the comparison of groups. Chi-square test was used for the analysis of quantitative data. P＜0.05 was taken as the statistical standard.

Results

There were 62 cases were cured, 14 cases were improved, and the total effective rate was 97.44% ( 76/78 ) in treatment group.There were 41 cases were cured, 20 cases were improved, and the total effective rate was 87.14% ( 61/70 ) in control group. There was a significant difference in effective rate between two groups (χ²=9.390, P＜0.05 ).There were significant differences in VAS pain score, pain disappearing time, scab and skin lesion subsided time between two groups ( t=2.582, 2.214, 2.107, 2.188, P＜0.05 ).

Conclusion

Ailanthus bark liquid has obvious curative effects on herpes zoster.