Recent advances in the application of traditional Chinese medicine in hypertension by intervening gut microbiota

doi:10.3877/cma.j.issn.2095-3240.2022.04.009

Abstract

Abstract:

The pathogenesis of hypertension has not been completely revealed. Recent studies have shown that the imbalance of gut microbiota is closely related to the occurrence and development of hypertension. Research progress of Chinese medicine monomers, Chinese medicine compounds and acupuncture in antagonizing hypertension and its risk factors was summarized with a focus on gut microbiota. It is expounded that traditional Chinese medicine(TCM)may treat hypertension and its risk factors by adjusting the abundance of some gut microbiota, improving abundance of probiotics or changing the levels of fermentation metabolites of gut microbiota(short-chain fatty acids, trimethylamine N-oxide, etc.). This provides more theoretical basis for TCM prevention and treatment of hypertension and its risk factors. Adjusting the imbalance of gut microbiota with TCM may be a new way to treat hypertension in the future.

Key words: Hypertension, Gastrointestinal microbiome, Medicine, Chinese traditional

Tian Li, Xiaoyue Cai, Juan Wang, Wei Zhou, Yingqiang Zhao. Recent advances in the application of traditional Chinese medicine in hypertension by intervening gut microbiota[J]. Chinese Journal of Acupuncture and Moxibustion(Electronic Edition), 2022, 11(04): 149-152.

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