针灸疗法是中医药的重要组成部分，因方便、有效、不良反应少被越来越多的国家认可。微环境在疾病的发生、发展及治疗、康复过程中起到至关重要的作用，已成为近年来多种疾病研究领域的热点。针灸对人体的治疗作用为始于微环境(腧穴)，又终于微环境(病灶)。许多关于针灸机制的研究报道是从针灸对不同系统或者不同部位微环境的影响角度对其进行阐述，选择骨关节炎、脊髓损伤、肿瘤等几个近年来研究报道频率较高的疾病来作一综述。

Acupuncture is an important part of traditional Chinese medicine, which is recognized by more and more countries for its convenience, effectiveness and fewer adverse reactions. Microenvironment plays an important role in the occurrence, development, treatment and rehabilitation of diseases, and it has become a hot spot in many research fields in recent years.The therapeutic effect of acupuncture on human body can be said to start from microenvironment (acupoints) and end with microenvironment (lesions). Some research reports on acupuncture mechanism are elaborated from the perspective of the influence of acupuncture on microenvironment in different systems or different parts. In this paper, several diseases with high frequency of research reports in recent years, such as osteoarthritis, spinal cord injury, and tumor, are reviewed.