目的

观察浮针疗法辅助治疗中晚期肿瘤患者中度癌痛的临床疗效。

方法

选择2012年1月至2014年1月山东省千佛山医院中医科及肿瘤放化疗科住院的中晚期不同肿瘤癌痛患者。将60例中度癌痛患者，按照随机数字表法分为联合治疗组及对照组各30例。联合治疗组在上述治疗基础上给予阿是穴周围浮针治疗1～2针，1次/d，24 h更换1次，连续观察14 d。对照组以硫酸吗啡缓释片30 mg为起始剂量口服，每12 h服药1次，根据疼痛程度调整并增加剂量，连续观察14 d。采用SPSS17.0统计分析软件进行统计学分析，两组治疗前后硫酸吗啡缓释片平均使用量，疼痛次数和治疗前、后QOL各项评分均为计量资料，采用两独立样本t检验；两组疗效比较，采用Wilcoxon秩和检验。以P＜0.05为差异有统计学意义。

结果

治疗第14天，联合治疗组当天硫酸吗啡缓释片使用量为（50.67±9.07）mg，对照组为（57.67±8.98）mg，两组比较差异有统计学意义（t=3.004，P＜0.05）；联合治疗组癌痛发作数为（0.77±0.63）次，而对照组为（1.10±0.64）次，两组比较差异有统计学意义（t=2.012，P＜0.05）；联合治疗组生活质量各项评分较对照组明显增加，差异均有统计学意义（t值分别为1.967、1.996、2.079、3.897、2.362、2.553，P均＜0.05）；联合治疗组30例患者中完全缓解患者15例，部分缓解患者12例，轻度缓解患者2例，无效1例，总有效率96.7%（29/30）；对照组30例患者中完全缓解者11例，部分缓解者9例，轻度缓解者5例，无效5例，总有效率83.3%（25/30），两组疗效比较差异有统计学意义（Z=1.724，P＜0.01）。

结论

浮针疗法可有效减少硫酸吗啡缓释片使用的剂量及减少肿瘤患者癌痛爆发次数，改善中晚期肿瘤患者的生活质量。

Objective

To observe the clinical curative effect of floating-needle supplementary therapy for moderate cancer pain in patients with middle and terminal stage of cancer.

Methods

Sixty patients of middle and terminal stage of cancer with moderate cancer pain were randomized into a floatingneedle therapy group and Western medicine group，30 cases in each one，who were selected from the department of traditional Chinese medicine and oncology Shandong Qianfoshan hospital ranging from January 2012 to January 2014.Western medicine group was given 30 mg/every 12 hrs with an initial dosage of 60 mg/day.The dosage was adjusted according to the relief of pain.The floating-needle therapy group was given floating-needle therapy，on the basis of above treatment.One or two needles were inserted at the sites 5 cm away from the pain point，which were manipulated and scattered subcutaneously.The treatment was given one time/per day.After 14-day treatment，the analgesic efficacy was observed by comparing the average dosage of MS-Contin，numbers of the outbreak of pain，quality of life and total effective rate between two groups.

Results

After 14-day-treatment，the dosage of MS-Contin was（50.67±9.07）mg in combined treatment group，while the dosage of MS-Contin was（57.67±8.98）mg in Western medicine group，there was a significant difference between the two groups（t=3.004，P＜0.05）.The outbreak of pain was（0.77±0.63）in the combined treatment group，while it was（1.10±0.64）in the Western medicine group，there was a significant difference between the two groups（t=2.012，P＜0.05）.The score of life quality was obviously improved in the combined treatment group compared with that of Western medicine group（t=1.967，1.996，2.079，3.897，2.362，2.553，all P＜0.05）.The total effective rate was 96.7%（29/30）in combined treatment group，and which was 83.3%（25/30）in the Western medicine group（Z=1.724，P＜0.01）.

Conclusion

The floating-needle therapy can effectively reduce the dosage of MS-Contin，reduce the number of the breakout of the pain，and improve the quality of life in patients with the middle and terminal stage of cancer.