目的

对痤疮相关临床随机对照试验（RCT） 进行Meta 分析， 从循证医学的角度分析火针治疗痤疮的疗效。

方法

利用计算机检索的方式， 全面收集2015 年12 月前针灸治疗痤疮的RCT文献。 两位研究者按照纳入与排除标准独立进行文献筛选、 资料提取、 质量评价和交叉审核后， 运用RevMan5.3 统计学软件进行统计学分析， 对比火针与抗生素类药物治疗痤疮的疗效优劣。

结果

共纳入7 篇高质量RCT， 合计965 例患者。 7 篇文献的治愈率合并RR=4.68， 95%CI （3.34， 6.55） ， 显效率合并RR=2.62， 95%CI （2.00， 3.34） ， 总有效率合并RR=1.16， 95%CI （1.11， 1.21） ， 火针组与西药（抗生素类药物）组在治愈率、显效率、总有效率方面比较，差异均有统计学意义（Z=8.98、6.97、6.53，P均＜0.00001。 未见火针治疗痤疮的不良反应报告。

结论

现阶段临床证据显示， 在治愈率、 显效率、总有效率方面， 火针治疗痤疮疗效优于西药（抗生素类药物） 。

Objective

Meta analysis was carried out on the relevant clinical randomized controlled trial （RCT）， which showed the curative effect of fire needle treatment for acne from the perspective evidence-based medicine.

Methods

Using the computer retrieval way， RCT data of acupuncture and moxibustion treatment of acne before December 2015 were collected. According to the inclusion and exclusion criteria，two researchers independently conducted literature screening，data extraction，quality evaluation and cross examination. RevMan5.3 was used for statistical analysis.The curative effects on acne were compared between fire needle and antibiotic drug treatment.

Results

A total of 7 highquality RCT were incorporated in this study including 965 patients. 7 studies and the cure rate of combined RR=4.68，95%CI（3.34，6.55） ，show the efficiency of merger RR=2.62，95%CI（2.00，3.34），total effective merger RR=1.16，95%CI（1.11，1.21） .Fire needle group and western medicine（antibiotics）on the cure rate，significant efficiency and total effective rate comparison，the differences were statistically significant（Z=8.98，6.97，6.53，P＜0.0001）.

Conclusion

Now the clinical evidence at this stage shows that fire needle treatment for acne is superior to antibiotic medicines in the cure rate，significant efficiency and total effective rate.