Clinical observation of electroacupuncture combined with platelet-rich plasma in the treatment of knee osteoarthritis

doi:10.3877/cma.j.issn.2095-3240.2024.01.004

Abstract

Abstract:

Objective

To observe the clinical effect of electroacupuncture combined with platelet-rich plasma (PRP) on knee osteoarthritis (KOA).

Methods

A total of 150 KOA patients from Handan Central Hospital from June 2018 to February 2022 were collected and divided into 61 patients in electroacupuncture group, 41 patients in PRP group and 48 patients in electroacupuncture+ PRP group according to different treatment protocols. The electroacupuncture treatment group was treated with electroacupuncture, the PRP group was treated with intra-articular injection of PRP, and the electroacupuncture+ PRP group was treated with electroacupuncture combined with PRP. All the continuous treatment lasted for five weeks. Visual Analogue Scale (VAS) scores, Lequesne index, Western Ontario McMaster University Osteoarthritis Index (WOMAC) scores and motion range of knee were compared before and after treatment in the three groups, and the clinical efficacy of the three groups was evaluated.

Results

After five weeks of treatment, VAS score, Lequesne index and WOMAC score in electroacupuncture + PRP group were lower than those in electroacupuncture and PRP group (t=15.925、28.116、16.710、19.822、12.641、15.912, all P<0.05). The motion of knee joint in electroacupuncture + PRP group was higher than that in electroacupuncture and PRP group (t=9.275、20.279, all P<0.05).

Conclusion

Electroacupuncture combined with PRP in the treatment of KOA is effective and worthy of clinical application.

Key words: Osteoarthritis, knee, Electroacupuncture, Platelet-rich plasma

Wei Xue, Shaoying Kang, Hongsheng Guo, Qingliang Gao, Yingmin Zhang, Yanping Gao. Clinical observation of electroacupuncture combined with platelet-rich plasma in the treatment of knee osteoarthritis[J]. Chinese Journal of Acupuncture and Moxibustion(Electronic Edition), 2024, 13(01): 13-17.

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Figures/Tables 5

References 15

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组别	例数	性别/例		年龄/岁			病程/月			Kellgren-Lawrence分级
组别	例数	男	女	最小	最大	平均（ ± s）	最小	最大	平均（ ± s）	Ⅰ	Ⅱ	Ⅲ
电针组	61	18	43	48	70	60.84 ± 5.42	6	25	12.65 ± 4.68	15	35	11
PRP组	41	13	28	45	72	61.46 ± 6.02	7	30	11.94 ± 3.84	11	24	6
电针+PRP组	48	15	33	47	69	59.24 ± 5.83	6	28	11.57 ± 4.05	13	28	7
统计值		χ²=1.026		t=0.074			t=0.081			χ²=0.283
P值		>0.05		>0.05			>0.05			>0.05

组别	例数	性别/例		年龄/岁			病程/月			Kellgren-Lawrence分级
组别	例数	男	女	最小	最大	平均（ ± s）	最小	最大	平均（ ± s）	Ⅰ	Ⅱ	Ⅲ
电针组	61	18	43	48	70	60.84 ± 5.42	6	25	12.65 ± 4.68	15	35	11
PRP组	41	13	28	45	72	61.46 ± 6.02	7	30	11.94 ± 3.84	11	24	6
电针+PRP组	48	15	33	47	69	59.24 ± 5.83	6	28	11.57 ± 4.05	13	28	7
统计值		χ²=1.026		t=0.074			t=0.081			χ²=0.283
P值		>0.05		>0.05			>0.05			>0.05

组别	例数	治疗前	治疗后	t值	P值
电针组	61	5.84±1.65	1.97±1.23	17.135	<0.05
PRP组	41	5.45±1.45	2.35±1.25	15.821	<0.05
电针＋PRP组	48	5.56±1.46	1.45±0.89^ab	24.461	<0.05
F值		1.203	127.21
P值		>0.05	<0.05

组别	例数	治疗前	治疗后	t值	P值
电针组	61	5.84±1.65	1.97±1.23	17.135	<0.05
PRP组	41	5.45±1.45	2.35±1.25	15.821	<0.05
电针＋PRP组	48	5.56±1.46	1.45±0.89^ab	24.461	<0.05
F值		1.203	127.21
P值		>0.05	<0.05

组别	例数	治疗前	治疗后	t值	P值
电针组	61	12.74±1.98	5.84±1.42	18.064	<0.05
PRP组	41	13.23±2.78	6.63±1.83	16.847	<0.05
电针＋PRP组	48	13.74±2.23	4.48±1.79^ab	26.512	<0.05
F值		1.685	73.126
P值		>0.05	<0.05

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